During oocyte maturation, Aurora B kinase regulates the stability of kinetochore-microtubule attachments by phosphorylating kinetochore proteins such as HEC1. Dysregulation of Aurora B activity leads ...

This valuable research advance builds upon previous studies to convincingly show that the centromere-histone core contributes to force transduction through the kinetochore. The centromere mainly ...

Centromeres are the site of assembly of the kinetochore, a proteinaceous structure that directs chromosome segregation during cell division. Active centromeres are characterized by the presence of ...

Kinetochore Structure: the proteins of this group assure the correct alignment of chromosomes during mitosis. Mitotic Spindle Dynamics: the proteins of this group regulate the spindle dynamics and ...