Antibodies (immunoglobins) are Y-shaped proteins produced by B cells of the immune system in response to exposure to antigens. Each antibody contains a paratope that recognizes a specific epitope on ...

An epitope is the part of an antigen that the host’s immune system recognizes, eliciting the immune response to an invading pathogen. It specifically binds to the corresponding antigen receptor ...

This library was used to map the epitopes of three polyclonal antibodies generated in three different rabbits using the same antigen, to evaluate differences in epitope patterns for the separate ...

Epitope Binning-seq, evaluates epitope similarity using genetically encoded query antibodies (qAbs) on antigen-expressing cells and next-generation sequencing (NGS), allowing simultaneous ...

Epitope Binning-seq, evaluates epitope similarity using genetically encoded query antibodies (qAbs) on antigen-expressing cells and next-generation sequencing (NGS), allowing simultaneous ...

In response to the evolving outbreak, JPT has developed a variety of novel, ready-to-use products for detailed and epitope-resolved detection and monitoring of antigen-specific immune responses.

However, the exact T cell epitopes and immunodominant antigen regions involved have not been fully determined. “Defining a comprehensive set of epitope specificities is important for several ...

LENS ai 's algorithm then looks at the atomic interactions between the antibody-antigen complexes to gain a better understanding of their binding specificity. In silico epitope binning powered by LENS ...

In a paper, "Epitope editing enables targeted immunotherapy ... When the immune system encounters foreign antigens (parts of pathogens or tumors), it tries to identify and neutralize them.

Now, a new strategy that leverages CRISPR to create CAR-Ts that target a ubiquitous antigen has shown potential ... put it in the release. Dubbed “epitope editing” by the researchers, the ...