In the benchmarking study, LENSai’s in silico epitope mapping application was tested across five known antibody-antigen pairs and against multiple experimental techniques, including HDX-MS ...

The advanced validation data, 3D Epitope Mapping, is designed to enhance the efficiency and accuracy of antibody-related selection, empowering scientists with the data they need to advance their ...

Merck & Co. has penned a $300 million biobucks-per-product deal with cancer biotech Epitopea to identify previously secret antigens that could form the backbone of off-the-shelf immunotherapies.

Research showed that healthy infants mount a robust IgG response to the same epitope. “Anti-flagellin reactivity has ... the findings in this study offer a biological target for the development of ...

Bispecific antibodies (bispecifics) can simultaneously target two distinct antigens or epitopes, offering novel therapeutic strategies such as enhancing immune cell targeting of cancer cells or ...

The seasonal influenza vaccine contains strains of viruses from distinct virus subtypes, but most people who are vaccinated will mount a strong immune response to one strain, leaving them ...

Researchers found that T cells recognize neoself-antigens -- abnormal, unfolded host proteins presented by major histocompatibility complex II (MHC-II) lacking the invariant chain -- as non-self ...

Epitope Binning-seq, evaluates epitope similarity using genetically encoded query antibodies (qAbs) on antigen-expressing cells and next-generation sequencing (NGS), allowing simultaneous ...

Epitope Binning-seq, evaluates epitope similarity using genetically encoded query antibodies (qAbs) on antigen-expressing cells and next-generation sequencing (NGS), allowing simultaneous ...

Long-term follow-up of ARI0002h (cesnicabtagene autoleucel), an academic point-of-care B-cell maturation antigen (BCMA)-directed chimeric antigen receptor (CAR) T-cell strategy: Activity and safety ...

In a paper, "Epitope editing enables targeted immunotherapy ... When the immune system encounters foreign antigens (parts of pathogens or tumors), it tries to identify and neutralize them.