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  1. Creutzfeldt-Jakob disease - Symptoms & causes - Mayo Clinic

    Jan 28, 2023 · Creutzfeldt-Jakob (KROITS-felt YAH-kobe) disease, also known as CJD, is a rare brain disorder that leads to dementia. It belongs to a group of human and animal diseases known as prion …

  2. Creutzfeldt–Jakob disease - Wikipedia

    Creutzfeldt–Jakob disease (CJD) is an incurable, invariably fatal, neurodegenerative disease belonging to the transmissible spongiform encephalopathy (TSE) group. [4][1] Early symptoms include memory …

  3. Clinical Overview of Creutzfeldt-Jakob Disease (CJD)

    Jan 21, 2026 · Creutzfeldt-Jakob disease (CJD) is a rapidly progressive and always fatal neurodegenerative disorder. It is believed to be caused by prions, which can cause abnormal folding …

  4. Creutzfeldt-Jakob Disease (CJD): Symptoms & Treatment

    May 15, 2025 · Creutzfeldt-Jakob disease is a degenerative brain disease caused by abnormal proteins (prions) that damage your brain. It’s usually fatal within a year.

  5. Creutzfeldt-Jakob disease (CJD) - Harvard Health

    Jun 13, 2025 · What is Creutzfeldt-Jakob disease? Creutzfeldt-Jakob disease (CJD) is a rare, fatal brain disorder caused by prions. Prions are normal proteins that have changed their shape. Healthy …

  6. About Creutzfeldt-Jakob Disease (CJD): Classic CJD Fact Sheet

    Oct 5, 2022 · Creutzfeldt-Jakob disease, or CJD, is a rare degenerative brain disease that is incurable and fatal. It is caused by prions, infectious, misshapen versions of normal proteins, which build up in …

  7. Creutzfeldt-Jakob Disease | CJD | MedlinePlus

    Dec 9, 2025 · Creutzfeldt-Jakob disease (CJD) is a rare, degenerative brain disorder. CJD progresses rapidly and is fatal. Learn how to prevent CJD.

  8. Creutzfeldt-Jakob Disease | National Institute of Neurological ...

    Mar 7, 2025 · Creutzfeldt-Jakob disease (CJD) is a rare, rapidly worsening brain disorder that causes unique changes in brain tissue and affects muscle coordination thinking, and memory.

  9. Creutzfeldt-Jakob Disease (CJD) - The Merck Manuals

    Creutzfeldt-Jakob disease (CJD) is a prion disease, which develops when a normal protein called cellular prion protein (PrPC) changes shape (misfolds) and becomes a disease-causing prion.

  10. Familial Prion Disease - Memory and Aging Center

    Genetic Creutzfeldt-Jakob disease (CJD) is a single gene disorder due to mutations in the prion gene (PRNP) on chromosome 20. Presently more than 20 alterations in the DNA sequence in the gene …