Jan 24, 2018 · Epithelial mesenchymal transition (EMT), an evolutionarily conserved developmental program, has been implicated in carcinogenesis and confers metastatic …

Feb 7, 2024 · Epithelial-to-mesenchymal transition (EMT), a biological phenomenon of cellular plasticity initially reported in embryonic development, has been increasingly recognized for its …

The current paradigm states that a few of the transformed cancer cells, presumably a few of the cancer progenitor cells, go through EMT to produce a metastatic form of cancer. This is a very …

EMT is also reversible by the mesenchymal-to-epithelial transition (MET), thought to affect circulating cancer cells when they reach a desirable metastatic niche to develop secondary …

Sep 8, 2022 · However, aberrant reactivation of EMT is associated with malignant properties of tumor cells during cancer progression and metastasis, including promoted migration and …

EMT allows the solid tumors to become more malignant, increasing their invasiveness and metastatic activity. Secondary tumors frequently maintain the typical histologic characteristics …

Aug 23, 2018 · Although EMT might promote cancer metastasis, the molecular mechanisms for it remain to be fully clarified. To address this issue, we constructed an EMT-metastasis gene …

Jan 12, 2018 · EMT-TFs play important roles in all stages of cancer progression from initiation, primary tumour growth, invasion, dissemination and metastasis to colonization as well as in …

Feb 7, 2024 · Epithelial-to-mesenchymal transition (EMT), a biological phenomenon of cellular plasticity initially reported in embryonic development, has been increasingly recognized for its …

Feb 26, 2015 · First, we compare embryogenesis and development with cancer metastasis. We then discuss the signaling pathways and the differential expression and down-regulation of …