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Drugs that make HIV-infected cells self-destruct induce ... - Aidsmap
May 3, 2024 · Last month’s Conference on Retroviruses and Opportunistic Infections (CROI 2024) included the latest information about potential drugs and treatments that might lead to a cure. Two presentations included promising data on TACK (targeted activation of cell kill). This is a property of some drugs in the non-nucleoside reverse transcriptase (NNRTI) family which induces a chain of events leading ...
Half the men in an HIV cure study stayed off treatment for nearly a ...
Mar 12, 2025 · The day before the Conference on Retroviruses and Opportunistic Infections (CROI 2025) opened in San Francisco on Sunday, there was a community workshop on HIV cure science, at which Dr Michael Peluso, a local HIV physician and cure researcher, flagged up two studies to look out for. “One is the RIO study,” he said. “This studied up to 70 people using a bnAb [broadly neutralising ...
How likely is mother-to-child transmission of HIV? - Aidsmap
Without any sort of treatment or care, the chance of a woman with HIV passing it on to her baby is considerable. Before antiretroviral therapy and other preventative measures were introduced, transmission rates per pregnancy were between 14 and 20% in European countries, and up to 43% in African countries.Transmission happened during pregnancy, around the …
CROI 2025: US funding freeze threatens two decades' …
Mar 13, 2025 · US funding freeze threatens two decades' progress in HIV Professor Chris Beyrer at CROI 2025. Photo by Roger Pebody. The global HIV response faces serious disruption due to cuts in US government funding, the closure of USAID, and uncertainty about future financing, warned Professor Chris Beyrer, Director of the Duke Global Health Institute, in his plenary address to the Conference on ...
Islatravir plus lenacapavir could be the first once-weekly oral HIV ...
Mar 6, 2024 · A once-weekly oral regimen can keep HIV suppressed as well as daily pills, according to study results presented today at the Conference on Retroviruses and Opportunistic Infections (CROI 2024).. In a phase II clinical trial, 94% of people who switched to weekly islatravir and lenacapavir pills maintained an undetectable viral load, matching the viral suppression rate of those who stayed on ...
CRISPR gene therapy EBT-101 does not prevent HIV viral rebound
May 14, 2024 · A CRISPR-based gene-editing therapy called EBT-101 was safe and well tolerated but did not prevent viral rebound in three participants who stopped antiretroviral treatment in an early study, according to a presentation last week at the American Society of Gene & Cell Therapy annual meeting.
Accessible HIV science is vital in an age of disinformation
Mar 3, 2025 · With deep regret the trustees of NAM Publications, publishers of aidsmap.com, decided in July 2024 that the charity was no longer financially sustainable. While honouring their commitment to staff, partners and service users, the trustees set about ensuring a longevity for the assets aidsmap had built up over four decades.
How much does HIV treatment cost the NHS? | aidsmap
In the UK, the most recent estimates of the lifetime cost of managing HIV range from £73,000 to £404,300, depending on whether branded or generic drugs are used. Since these are averages, the actual lifetime cost of treating someone for HIV will vary depending on the year and their age when they were diagnosed, whether they were diagnosed …
Injectable HIV treatment underway in England and largely
May 8, 2024 · Injectable HIV antiretroviral therapy (ART) is starting to be provided in England with several hundred patients now on the two-monthly injections. The British HIV Association (BHIVA) Spring Conference in Birmingham last week heard some of the first data from the rollout in England. In general, the injections are effective and liked by patients, though there have been a few withdrawals.