An Introduction to Transfection, Transfection Protocol and …
May 10, 2024 · In 1928, Griffith proposed the “transforming principle” having observed that bacterial cells could take up foreign hereditary genetic material. 1 This led to the discovery of DNA as that genetic material, 2 a discovery that enabled great strides in science. In the 1960s, viruses were employed to transfer genetic material into animal cells in …
IR Spectroscopy and FTIR Spectroscopy: How an FTIR …
Apr 12, 2024 · The human eye can only see a small part of the much broader spectrum of electromagnetic radiation (Figure 1). On the high-energy side of the visible spectrum lies the ultraviolet (UV) region, while on the lower energy side is the infrared (IR).
Next-Generation Sequencing (NGS): Definition and Overview
Oct 28, 2024 · With these immense technological advances, the human genome project was completed in 2003. 9 In 2005, the first commercially available NGS platform, or second generation (2G) as it has become, was introduced, able to amplify millions of copies of a particular DNA fragment in a massively paralleled way in contrast to Sanger sequencing. 10 …
Neuroimaging Techniques and What a Brain Image Can Tell Us
Apr 8, 2024 · Neuroimaging is a discipline that deals with the in vivo depiction of the structure, function and pharmacology of the central nervous system (CNS), particularly our brain, in a noninvasive manner. 1, 2 The past two decades have witnessed remarkable strides in the development of new anatomical and functional imaging techniques that can shed light on many critical aspects of human brain function ...
Mann-Whitney U Test: Assumptions and Example - Technology …
Mar 25, 2024 · The Mann-Whitney U Test, also known as the Wilcoxon Rank Sum Test, is a non-parametric statistical test used to compare two samples or groups. In this article, we explore the basics of the Test and work through an example.
Understanding Single-Cell Sequencing, How It Works and Its …
Feb 26, 2024 · Traditional next-generation sequencing (NGS) examines the genome of a cell population, such as a cell culture, a tissue, an organ or an entire organism.Its output is the “average genome” of the cell population. On the other hand, single-cell sequencing measures the genomes of individual cells from a cell population. 5 Nowadays, traditional methods are thus referred to as bulk sequencing to ...
Understanding Battery Types, Components and the Role of Battery ...
May 30, 2024 · Batteries are perhaps the most prevalent and oldest forms of energy storage technology in human history. 4 Nonetheless, it was not until 1749 that the term "battery" was coined by Benjamin Franklin to describe several capacitors (known as Leyden jars, after the town in which it was discovered), connected in series. The term "battery" was presumably chosen based on the analogy to existing ...
B Cells, Memory B Cells and Plasma Cells: B Cell Activation ...
Mar 19, 2024 · B cells, also known as B lymphocytes, are immune cells that drive the humoral adaptive immune response.They are one of three types of lymphocyte in the adaptive immune response – the others being T cells and natural killer (NK) cells. 1 B cells are distinguished by their ability to produce antibodies (known as immunoglobulins (Ig) when attached to B cells via a transmembrane domain), and the ...
Genetic Modification Techniques and Applications
Jan 4, 2024 · As mentioned, different types of genetic modification can be made, including: Gene knockout – the removal or inactivation of a target gene.; Deletion mutation – the removal of one or more nucleotides from a genetic sequence.; Insertion mutation – the addition of one or more nucleotides into a genetic sequence.; Substitution mutation – the switching out of one or more nucleotides in a ...
An Introduction to the Lateral Flow Test: Strengths, Limitations and ...
May 2, 2024 · Diagnostic testing is key in many areas including healthcare and preventative medicine, food safety and environmental monitoring. As such, analysts need appropriate and accurate assays suited to the sample type, analyte and testing environment that respect monetary, time and operator constraints.