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Good Benefits of using a Pacifier Pacifiers satisfy an infant’s innate non-nutritive sucking reflex, which has a calming effect and helps regulate stress and self-soothing.. Clinical studies associate pacifier use during sleep with a reduced risk of Sudden Infant Death Syndrome (SIDS), possibly by improving airway patency and increasing arousal from sleep. Pacifiers can also aid sleep onset, reduce crying, and provide comfort without unnecessary feeding. Compared to thumb-sucking, pacifier use i