Do opossums make noise? Depends on what we’re eating 🌝❤️🎃🌻🌼🐢🌿💕 Opossums are relatively quiet animals! There are, however, a few noises opossums make. When frightened, they hiss and growl. When seeking a mate or calling to their babies, they make a clicking noise from the sides of their mouths. When looking for their mother, babies make a quick, sharp “sneeze” that sounds like a little lawn sprinkler. And big opossums will even snore sometimes!! Every once in a while an opossum will cough